The research was published online Dec. 12 in Nature Medicine.

"This is a major breakthrough in understanding the development and treatment of kidney disease associated with proteinuria, the leakage of protein in the urine," said the study's lead author Sumant Singh Chugh, M.D., associate professor of medicine in the UAB Division of Nephrology.

Nephrotic syndrome is characterized by the presence of excessive protein in the urine, low blood-protein levels, high cholest...

Hepatitis C virus infects the liver and leads to serious permanent liver damage. The infection affects about 170 million people worldwide and up to 500,000 people in the UK. Most people who come into contact with HCV contract a long-term or chronic infection and, as a consequence, run a significant risk of liver failure - necessitating liver transplantation - or liver cancer.

The new multi-centre study was jointly led by researchers from the University of Southampton's School of M...

The pilot study, which included senior researchers from the University of Pittsburgh Graduate School of Public Health (GSPH), the Cooper Institute in Dallas, Stanford University, Wake Forest University and the University of Florida, involved administering a structured physical activity consisting primarily of walking at a moderate intensity for at least 150 minutes a week, coupled with leg stretches, balance exercises and leg-strengthening exercises, to a group of sedentary elderly people age...

For almost a hundred years mounting epidemiological evidence has linked alcohol use to an increased risk of cancers of the stomach, esophagus, liver, breast, and colon. Researchers have never developed an adequate model to explain how ethanol or a metabolite of ethanol may cause cancer. Hypotheses abound, and include such diverse theories as acetaldehyde carcinogenicity, dietary imbalances, and impaired nutrient metabolism and detoxification due to alcohol consumption, activation of precancer...

"Encompassing 60 percent of all research money to universities, the academic, life-science research enterprise is large and growing, representing $28.8 billion in research and development expenditures in 2006," the authors write as background information in the article. "To establish policies and priorities, a better empirical picture is needed of what the academic medical center (AMC) research enterprise looks like, but beyond generic classifications such as 'basic' and 'a...

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